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Muscle‐derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress
Mitochondrial dysfunction promotes metabolic stress responses in a cell‐autonomous as well as organismal manner. The wasting hormone growth differentiation factor 15 (GDF15) is recognized as a biomarker of mitochondrial disorders, but its pathophysiological function remains elusive. To test the hypo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054681/ https://www.ncbi.nlm.nih.gov/pubmed/32026535 http://dx.doi.org/10.15252/embr.201948804 |