Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV

There is a clear need for low-cost, self-applied, long-lasting approaches to prevent human immunodeficiency virus (HIV) infection in both men and women, even with the advent of pre-exposure prophylaxis (PrEP). Broadly neutralizing antibodies represent an option to improve HIV prophylaxis, but intrav...

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Detalles Bibliográficos
Autores principales: Lindsay, Kevin E., Vanover, Daryll, Thoresen, Merrilee, King, Heath, Xiao, Peng, Badial, Peres, Araínga, Mariluz, Park, Seong Bin, Tiwari, Pooja M., Peck, Hannah E., Blanchard, Emmeline L., Feugang, Jean M., Olivier, Alicia K., Zurla, Chiara, Villinger, Francois, Woolums, Amelia R., Santangelo, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054722/
https://www.ncbi.nlm.nih.gov/pubmed/31995741
http://dx.doi.org/10.1016/j.ymthe.2020.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054722/
https://www.ncbi.nlm.nih.gov/pubmed/31995741
http://dx.doi.org/10.1016/j.ymthe.2020.01.002

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