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The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets

Autophagy is a critical cellular homeostatic mechanism, the dysfunction of which has been linked to a wide variety of disease states. It is regulated through the activity of specific kinases, in particular Unc-51 like autophagy activating kinase 1 (ULK1) and Phosphatidylinositol 3-kinase vacuolar pr...

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Detalles Bibliográficos
Autores principales: Zachari, Maria, Rainard, Julie M., Pandarakalam, George C., Robinson, Lindsay, Gillespie, Jonathan, Rajamanickam, Muralikrishnan, Hamon, Veronique, Morrison, Angus, Ganley, Ian G., McElroy, Stuart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054748/
https://www.ncbi.nlm.nih.gov/pubmed/32011652
http://dx.doi.org/10.1042/BCJ20190846