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The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets
Autophagy is a critical cellular homeostatic mechanism, the dysfunction of which has been linked to a wide variety of disease states. It is regulated through the activity of specific kinases, in particular Unc-51 like autophagy activating kinase 1 (ULK1) and Phosphatidylinositol 3-kinase vacuolar pr...
Autores principales: | Zachari, Maria, Rainard, Julie M., Pandarakalam, George C., Robinson, Lindsay, Gillespie, Jonathan, Rajamanickam, Muralikrishnan, Hamon, Veronique, Morrison, Angus, Ganley, Ian G., McElroy, Stuart P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054748/ https://www.ncbi.nlm.nih.gov/pubmed/32011652 http://dx.doi.org/10.1042/BCJ20190846 |
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