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Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a
Discovered as an adaptive immune system of prokaryotes, CRISPR–Cas provides many promising applications. DNA-cleaving Cas enzymes like Cas9 and Cas12a, are of great interest for genome editing. The specificity of these DNA nucleases is determined by RNA guides, providing great targeting adaptability...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054755/ https://www.ncbi.nlm.nih.gov/pubmed/31872209 http://dx.doi.org/10.1042/BST20190563 |