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A Functional Polymorphism in the Promoter Region of Interleukin-12B Increases the Risk of Colorectal Cancer

OBJECTIVE: To investigate whether the polymorphisms of interleukin-12B (IL-12B) were associated with the risk of developing colorectal cancer (CRC). Patients and Methods. Genotypes of rs17860508 and rs3212227 were determined by polymerase chain reaction with a direct sequencing method in 329 CRC pat...

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Detalles Bibliográficos
Autores principales: Liu, Yabin, Li, Binghui, Wang, Lili, Kong, Dexian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054766/
https://www.ncbi.nlm.nih.gov/pubmed/32149085
http://dx.doi.org/10.1155/2020/2091781