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Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin

Stomatin (STOM) is a monotopic integral membrane protein found in all classes of life that has been shown to regulate members of the acid-sensing ion channel (ASIC) family. However, the mechanism by which STOM alters ASIC function is not known. Using chimeric channels, we combined patch-clamp electr...

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Detalles Bibliográficos
Autores principales: Klipp, Robert C., Cullinan, Megan M., Bankston, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054857/
https://www.ncbi.nlm.nih.gov/pubmed/32012213
http://dx.doi.org/10.1085/jgp.201912471