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Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin
Stomatin (STOM) is a monotopic integral membrane protein found in all classes of life that has been shown to regulate members of the acid-sensing ion channel (ASIC) family. However, the mechanism by which STOM alters ASIC function is not known. Using chimeric channels, we combined patch-clamp electr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054857/ https://www.ncbi.nlm.nih.gov/pubmed/32012213 http://dx.doi.org/10.1085/jgp.201912471 |