Cargando…
Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin
Stomatin (STOM) is a monotopic integral membrane protein found in all classes of life that has been shown to regulate members of the acid-sensing ion channel (ASIC) family. However, the mechanism by which STOM alters ASIC function is not known. Using chimeric channels, we combined patch-clamp electr...
Autores principales: | Klipp, Robert C., Cullinan, Megan M., Bankston, John R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054857/ https://www.ncbi.nlm.nih.gov/pubmed/32012213 http://dx.doi.org/10.1085/jgp.201912471 |
Ejemplares similares
-
Regulation of acid-sensing ion channels by protein binding partners
por: Cullinan, Megan M., et al.
Publicado: (2021) -
Dynamic landscape of the intracellular termini of acid-sensing ion channel 1a
por: Cullinan, Megan M., et al.
Publicado: (2023) -
Structural determinants of acid-sensing ion channel potentiation by single chain lipids
por: Klipp, Robert C., et al.
Publicado: (2022) -
Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1
por: Kozlenkov, Alexey, et al.
Publicado: (2014) -
A stomatin dimer modulates the activity of acid-sensing ion channels
por: Brand, Janko, et al.
Publicado: (2012)