Parvalbumin Interneuron Dysfunction in a Thalamo-Prefrontal Cortical Circuit in Disc1 Locus Impairment Mice

Altered cortical excitation-inhibition (E-I) balance resulting from abnormal parvalbumin interneuron (PV IN) function is a proposed pathophysiological mechanism of schizophrenia and other major psychiatric disorders. Preclinical studies have indicated that disrupted-in-schizophrenia-1 (Disc1) is a u...

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Detalles Bibliográficos
Autores principales: Delevich, Kristen, Jaaro-Peled, Hanna, Penzo, Mario, Sawa, Akira, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054897/
https://www.ncbi.nlm.nih.gov/pubmed/32029441
http://dx.doi.org/10.1523/ENEURO.0496-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054897/
https://www.ncbi.nlm.nih.gov/pubmed/32029441
http://dx.doi.org/10.1523/ENEURO.0496-19.2020

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