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PPAR γ/TLR4/TGF-β1 axis mediates the protection effect of erythropoietin on cyclosporin A-induced chronic nephropathy in rat

OBJECTIVE: Nephrotoxicity is the main side effect of cyclosporine A and finding an effective combating method is urgent. The present study investigates the improving effect of erythropoietin (EPO) on cyclosporine A induce renal injury in rats and further explores its possible mechanism. METHODS: Rec...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Tan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054967/
https://www.ncbi.nlm.nih.gov/pubmed/32090669
http://dx.doi.org/10.1080/0886022X.2020.1729188