Cargando…

PPAR γ/TLR4/TGF-β1 axis mediates the protection effect of erythropoietin on cyclosporin A-induced chronic nephropathy in rat

OBJECTIVE: Nephrotoxicity is the main side effect of cyclosporine A and finding an effective combating method is urgent. The present study investigates the improving effect of erythropoietin (EPO) on cyclosporine A induce renal injury in rats and further explores its possible mechanism. METHODS: Rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Bin, Tan, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054967/ https://www.ncbi.nlm.nih.gov/pubmed/32090669 http://dx.doi.org/10.1080/0886022X.2020.1729188

Ejemplares similares

Omega-3 fatty acid decreases oleic acid by decreasing SCD-1 expression in the liver and kidney of a cyclosporine-induced nephropathy rat model
por: Lee, Su Mi, et al.
Publicado: (2019)

Combination of leflunomide and benazepril reduces renal injury of diabetic nephropathy rats and inhibits high-glucose induced cell apoptosis through regulation of NF-κB, TGF-β and TRPC6
por: Li, Huili, et al.
Publicado: (2019)

The protective effect and mechanism of rapamycin in the rat model of IgA nephropathy
por: Guo, Ning, et al.
Publicado: (2019)

Novel lncRNA XLOC_032768 protects against renal tubular epithelial cells apoptosis in renal ischemia–reperfusion injury by regulating FNDC3B/TGF-β1
por: Zhou, Xiangjun, et al.
Publicado: (2020)

Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-β1/Smad pathway in MN mice
por: Li, Yongzhang, et al.
Publicado: (2023)

DMP-1 attenuates oxidative stress and inhibits TGF-β activation in rats with diabetic kidney disease
por: Du, Na, et al.
Publicado: (2016)

A new update for radiocontrast-induced nephropathy aggravated with glycerol in rats: the protective potential of epigallocatechin-3-gallate
por: Palabiyik, Saziye Sezin, et al.
Publicado: (2017)

H(2)S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression
por: Li, Yan, et al.
Publicado: (2016)

High glucose and TGF-β1 reduce expression of endoplasmic reticulum-resident selenoprotein S and selenoprotein N in human mesangial cells
por: Huang, Fumeng, et al.
Publicado: (2019)

Interleukin-22 attenuates renal tubular cells inflammation and fibrosis induced by TGF-β1 through Notch1 signaling pathway
por: Tang, Rong, et al.
Publicado: (2020)

Effects of autophagy on macrophage adhesion and migration in diabetic nephropathy
por: Jiang, Yuteng, et al.
Publicado: (2019)

The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway
por: Liu, Lei, et al.
Publicado: (2018)

Hirudin ameliorates immunoglobulin A nephropathy by inhibition of fibrosis and inflammatory response
por: Deng, Fei, et al.
Publicado: (2019)

The role of oxidative stress-mediated apoptosis in the pathogenesis of uric acid nephropathy
por: Yang, Lijuan, et al.
Publicado: (2019)

The gut microbiome in differential diagnosis of diabetic kidney disease and membranous nephropathy
por: Yu, Wei, et al.
Publicado: (2020)

Mesenchymal stem cells: a future experimental exploration for recession of diabetic nephropathy
por: Hamza, Amal H., et al.
Publicado: (2016)

Curcumin modulates gut microbiota and improves renal function in rats with uric acid nephropathy
por: Xu, Xueling, et al.
Publicado: (2021)

Intermedin protects HUVECs from ischemia reperfusion injury via Wnt/β-catenin signaling pathway
por: Wang, Yanhong, et al.
Publicado: (2019)

Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats
por: Maheshwari, Rajesh, et al.
Publicado: (2016)

Correlation analysis between expression of histone deacetylase 6 and clinical parameters in IgA nephropathy patients
por: Hu, Yan, et al.
Publicado: (2021)

Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy
por: Gan, Lu, et al.
Publicado: (2018)

ATF4-dependent heme-oxygenase-1 attenuates diabetic nephropathy by inducing autophagy and inhibiting apoptosis in podocyte
por: Yuan, Shizhu, et al.
Publicado: (2021)

The inhibition of Nrf2 accelerates renal lipid deposition through suppressing the ACSL1 expression in obesity-related nephropathy
por: Chen, Yinyin, et al.
Publicado: (2019)

Salvia przewalskii extract of total phenolic acids inhibit TLR4 signaling activation in podocyte injury induced by puromycin aminonucleoside in vitro
por: Ren, Hongqi, et al.
Publicado: (2018)

Atorvastatin attenuates experimental contrast-induced acute kidney injury: a role for TLR4/MyD88 signaling pathway
por: Yue, Rongzheng, et al.
Publicado: (2017)

The miR-15a-5p-XIST-CUL3 regulatory axis is important for sepsis-induced acute kidney injury
por: Xu, Guanhua, et al.
Publicado: (2019)

TNF-α-mediated podocyte injury via the apoptotic death receptor pathway in a mouse model of IgA nephropathy
por: Wan, Qiang, et al.
Publicado: (2022)

Decreased expression of transforming growth factor-β1 and α-smooth muscle actin contributes to the protection of lotensin against chronic renal failure in rats
por: Xiao, Qingfei, et al.
Publicado: (2018)

Investigation of mechanisms of mesenchymal stem cells for treatment of diabetic nephropathy via construction of a miRNA-TF-mRNA network
por: Yang, Hailing, et al.
Publicado: (2018)

Yishen capsule promotes podocyte autophagy through regulating SIRT1/NF-κB signaling pathway to improve diabetic nephropathy
por: Liu, Yuxiang, et al.
Publicado: (2021)

MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway
por: Cheng, Li, et al.
Publicado: (2022)

The renoprotective effect of curcumin against cisplatin-induced acute kidney injury in mice: involvement of miR-181a/PTEN axis
por: Huang, Si-Jia, et al.
Publicado: (2020)

Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model
por: Thomsen, Lise Høj, et al.
Publicado: (2017)

Changes E3 ubiquitin protein ligase 1 gene mRNA expression correlated with IgA1 glycosylation in patients with IgA nephropathy
por: Liu, Youxia, et al.
Publicado: (2019)

Anti-pentraxin 3 auto-antibodies might be protective in lupus nephritis: a large cohort study
por: Yuan, Mo, et al.
Publicado: (2017)

Atorvastatin protects against contrast-induced acute kidney injury via upregulation of endogenous hydrogen sulfide
por: Yan, Lin, et al.
Publicado: (2020)

Protective effect of bone marrow mesenchymal stem cells modified with klotho on renal ischemia-reperfusion injury
por: Xie, Li-Bo, et al.
Publicado: (2019)

Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) overexpression alleviates endoplasmic reticulum stress after acute kidney injury
por: Pan, Hao, et al.
Publicado: (2022)

MiR-122-5p promotes peritoneal fibrosis in a rat model of peritoneal dialysis by targeting Smad5 to activate Wnt/β-catenin pathway
por: Liu, Yirong, et al.
Publicado: (2022)

The miR-26a-5p/IL-6 axis alleviates sepsis-induced acute kidney injury by inhibiting renal inflammation
por: Chen, Yanhong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sg12oimpobmslri24e84osrco4