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Heparan sulfate is a clearance receptor for aberrant extracellular proteins

The accumulation of aberrant proteins leads to various neurodegenerative disorders. Mammalian cells contain several intracellular protein degradation systems, including autophagy and proteasomal systems, that selectively remove aberrant intracellular proteins. Although mammals contain not only intra...

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Detalles Bibliográficos
Autores principales: Itakura, Eisuke, Chiba, Momoka, Murata, Takeshi, Matsuura, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054991/
https://www.ncbi.nlm.nih.gov/pubmed/32211892
http://dx.doi.org/10.1083/jcb.201911126