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Heparan sulfate is a clearance receptor for aberrant extracellular proteins
The accumulation of aberrant proteins leads to various neurodegenerative disorders. Mammalian cells contain several intracellular protein degradation systems, including autophagy and proteasomal systems, that selectively remove aberrant intracellular proteins. Although mammals contain not only intra...
Autores principales: | Itakura, Eisuke, Chiba, Momoka, Murata, Takeshi, Matsuura, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054991/ https://www.ncbi.nlm.nih.gov/pubmed/32211892 http://dx.doi.org/10.1083/jcb.201911126 |
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