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Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
Phosphatidic acid (PA) is both a central phospholipid biosynthetic intermediate and a multifunctional lipid second messenger produced at several discrete subcellular locations. Organelle-specific PA pools are believed to play distinct physiological roles, but tools with high spatiotemporal control a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054994/ https://www.ncbi.nlm.nih.gov/pubmed/31999306 http://dx.doi.org/10.1083/jcb.201907013 |