Differential turnover of Nup188 controls its levels at centrosomes and role in centriole duplication

NUP188 encodes a scaffold component of the nuclear pore complex (NPC) and has been implicated as a congenital heart disease gene through an ill-defined function at centrioles. Here, we explore the mechanisms that physically and functionally segregate Nup188 between the pericentriolar material (PCM)...

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Detalles Bibliográficos
Autores principales: Vishnoi, Nidhi, Dhanasekeran, Karthigeyan, Chalfant, Madeleine, Surovstev, Ivan, Khokha, Mustafa K., Lusk, C. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055002/
https://www.ncbi.nlm.nih.gov/pubmed/32211895
http://dx.doi.org/10.1083/jcb.201906031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055002/
https://www.ncbi.nlm.nih.gov/pubmed/32211895
http://dx.doi.org/10.1083/jcb.201906031

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