Cargando…
Differential turnover of Nup188 controls its levels at centrosomes and role in centriole duplication
NUP188 encodes a scaffold component of the nuclear pore complex (NPC) and has been implicated as a congenital heart disease gene through an ill-defined function at centrioles. Here, we explore the mechanisms that physically and functionally segregate Nup188 between the pericentriolar material (PCM)...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055002/ https://www.ncbi.nlm.nih.gov/pubmed/32211895 http://dx.doi.org/10.1083/jcb.201906031 |