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Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation

Memory and learning involve activity-driven expression of proteins and cytoskeletal reorganization at new synapses, requiring posttranscriptional regulation of localized mRNA a long distance from corresponding nuclei. A key factor expressed early in synapse formation is Msp300/Nesprin-1, which organ...

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Detalles Bibliográficos
Autores principales: Titlow, Joshua, Robertson, Francesca, Järvelin, Aino, Ish-Horowicz, David, Smith, Carlas, Gratton, Enrico, Davis, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055005/
https://www.ncbi.nlm.nih.gov/pubmed/32040548
http://dx.doi.org/10.1083/jcb.201903135