Chitinase 3 like 1 suppresses the stability and activity of p53 to promote lung tumorigenesis

BACKGROUND: Chitinase 3 like 1 protein (Chi3L1) is expressed in several cancers, and a few evidences suggest that the secreted Chi3L1 contributes to tumor development. However, the molecular mechanisms of intracellular Chi3L1 are unknown in the lung tumor development. Methods: In the present study,...

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Detalles Bibliográficos
Autores principales: Park, Kyung-Ran, Yun, Hyung-Mun, Yoo, Kyeongwon, Ham, Young Wan, Han, Sang Bae, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055043/
https://www.ncbi.nlm.nih.gov/pubmed/32127023
http://dx.doi.org/10.1186/s12964-019-0503-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055043/
https://www.ncbi.nlm.nih.gov/pubmed/32127023
http://dx.doi.org/10.1186/s12964-019-0503-7

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