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MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer

BACKGROUND: Long noncoding RNAs (lncRNAs) are emerging as critical regulatory elements and play fundamental roles in the biology of various cancers. However, we are still lack of knowledge about their expression patterns and functions in human colorectal cancer (CRC). METHODS: Differentially express...

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Detalles Bibliográficos
Autores principales: Xu, Juan, Shao, Tingting, Song, Mingxu, Xie, Yunjin, Zhou, Jialiang, Yin, Jiaqi, Ding, Na, Zou, Haozhe, Li, Yongsheng, Zhang, Jiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055097/
https://www.ncbi.nlm.nih.gov/pubmed/32127004
http://dx.doi.org/10.1186/s12943-020-01174-w