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High Expression of Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) in Esophageal Squamous Cell Carcinoma and its Clinical Prognostic Significance

BACKGROUND: Recently, targeted therapy for malignant tumors has developed rapidly, but there is still no effective targeted therapy for advanced esophageal squamous cell carcinoma (ESCC). Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a key enzyme involved in folate metabolism and is closely...

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Detalles Bibliográficos
Autores principales: He, Huan, Li, Peng-Cheng, Jia, Wei, Hu, Bing, Ji, Chu-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055195/
https://www.ncbi.nlm.nih.gov/pubmed/32088725
http://dx.doi.org/10.12659/MSM.920259