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Pregabalin inhibits in vivo and in vitro cytokine secretion and attenuates spleen inflammation in Lipopolysaccharide/Concanavalin A -induced murine models of inflammation

Immune system alteration has been implicated in the pathogenesis of chronic pain conditions, epilepsy and generalized anxiety disorder. Targeting cytokines has recently been proposed for the management of such conditions. Pregabalin (PGB) is an antiepileptic agent used for the management of these co...

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Detalles Bibliográficos
Autores principales: Abu-rish, Eman Y., Mansour, Ahmad T., Mansour, Hebah T., Dahabiyeh, Lina A., Aleidi, Shereen M., Bustanji, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055236/
https://www.ncbi.nlm.nih.gov/pubmed/32132609
http://dx.doi.org/10.1038/s41598-020-61006-1