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Pregabalin inhibits in vivo and in vitro cytokine secretion and attenuates spleen inflammation in Lipopolysaccharide/Concanavalin A -induced murine models of inflammation
Immune system alteration has been implicated in the pathogenesis of chronic pain conditions, epilepsy and generalized anxiety disorder. Targeting cytokines has recently been proposed for the management of such conditions. Pregabalin (PGB) is an antiepileptic agent used for the management of these co...
Autores principales: | Abu-rish, Eman Y., Mansour, Ahmad T., Mansour, Hebah T., Dahabiyeh, Lina A., Aleidi, Shereen M., Bustanji, Yasser |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055236/ https://www.ncbi.nlm.nih.gov/pubmed/32132609 http://dx.doi.org/10.1038/s41598-020-61006-1 |
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