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Deletion of metal transporter Zip14 (Slc39a14) produces skeletal muscle wasting, endotoxemia, Mef2c activation and induction of miR-675 and Hspb7

Skeletal muscle represents the largest pool of body zinc, however, little is known about muscle zinc homeostasis or muscle-specific zinc functions. Zip14 (Slc39a14) was the most highly expressed zinc transporter in skeletal muscle of mice in response to LPS-induced inflammation. We compared metaboli...

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Detalles Bibliográficos
Autores principales: Kim, Jinhee, Aydemir, Tolunay Beker, Jimenez-Rondan, Felix R., Ruggiero, Courtney H., Kim, Min-Hyun, Cousins, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055249/
https://www.ncbi.nlm.nih.gov/pubmed/32132660
http://dx.doi.org/10.1038/s41598-020-61059-2