Cargando…

Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses

Flaviviridae infections represent a major global health burden. By deciphering mechanistic aspects of hepatitis C virus (HCV)-host interactions, one could discover common strategy for inhibiting the replication of related flaviviruses. By elucidating the HCV interactome, we identified the 17-beta-hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamed, Bassim, Mazeaud, Clément, Baril, Martin, Poirier, Donald, Sow, Aïssatou Aïcha, Chatel-Chaix, Laurent, Titorenko, Vladimir, Lamarre, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055353/
https://www.ncbi.nlm.nih.gov/pubmed/32132633
http://dx.doi.org/10.1038/s41598-020-61051-w