Structure of the MICU1–MICU2 heterodimer provides insights into the gatekeeping threshold shift

Mitochondrial calcium uptake proteins 1 and 2 (MICU1 and MICU2) mediate mitochondrial Ca(2+) influx via the mitochondrial calcium uniporter (MCU). Its molecular action for Ca(2+) uptake is tightly controlled by the MICU1–MICU2 heterodimer, which comprises Ca(2+) sensing proteins which act as gatekee...

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Detalles Bibliográficos
Autores principales: Park, Jongseo, Lee, Youngjin, Park, Taein, Kang, Jung Youn, Mun, Sang A, Jin, Minwoo, Yang, Jihyeong, Eom, Soo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055370/
https://www.ncbi.nlm.nih.gov/pubmed/32148862
http://dx.doi.org/10.1107/S2052252520001840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055370/
https://www.ncbi.nlm.nih.gov/pubmed/32148862
http://dx.doi.org/10.1107/S2052252520001840

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