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Early-Life Stress Induces Depression-Like Behavior and Synaptic-Plasticity Changes in a Maternal Separation Rat Model: Gender Difference and Metabolomics Study

More than 300 million people suffer from depressive disorders globally. People under early-life stress (ELS) are reportedly vulnerable to depression in their adulthood, and synaptic plasticity can be the molecular mechanism underlying such depression. Herein, we simulated ELS by using a maternal sep...

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Detalles Bibliográficos
Autores principales: Cui, Yongfei, Cao, Kerun, Lin, Huiyuan, Cui, Sainan, Shen, Chongkun, Wen, Wenhao, Mo, Haixin, Dong, Zhaoyang, Bai, Shasha, Yang, Lei, Shi, Yafei, Zhang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055479/
https://www.ncbi.nlm.nih.gov/pubmed/32174832
http://dx.doi.org/10.3389/fphar.2020.00102