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SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism

SLC25A32 is a member of the solute carrier 25 family of mitochondrial transporters. SLC25A32 transports tetrahydrofolate (THF) as well as FAD into mitochondria and regulates mitochondrial one-carbon metabolism and redox balance. While it is known that cancer cells require one-carbon and FAD-dependen...

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Detalles Bibliográficos
Autores principales: Santoro, Valeria, Kovalenko, Ilya, Vriens, Kim, Christen, Stefan, Bernthaler, Andreas, Haegebarth, Andrea, Fendt, Sarah-Maria, Christian, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055544/
https://www.ncbi.nlm.nih.gov/pubmed/32166001
http://dx.doi.org/10.18632/oncotarget.27486