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Methylation Status of the Nanog Promoter Determines the Switch between Cancer Cells and Cancer Stem Cells

Cancer stem cells (CSCs) are the main cause of tumor development, metastasis, and relapse. CSCs are thus considered promising targets for cancer therapy. However, it is hard to eradicate CSCs due to their inherent plasticity and heterogeneity, and the underlying mechanism of the switch between non‐C...

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Detalles Bibliográficos
Autores principales: Liu, Shupeng, Cheng, Kai, Zhang, Hui, Kong, Ruijiao, Wang, Shuo, Mao, Chuanbin, Liu, Shanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055559/
https://www.ncbi.nlm.nih.gov/pubmed/32154082
http://dx.doi.org/10.1002/advs.201903035