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Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease
The influence of environmental insults on the onset and progression of mitochondrial diseases is unknown. To evaluate the effects of infection on mitochondrial disease we used a mouse model of Leigh Syndrome, where a missense mutation in the Taco1 gene results in the loss of the translation activato...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055822/ https://www.ncbi.nlm.nih.gov/pubmed/32130224 http://dx.doi.org/10.1371/journal.pgen.1008604 |