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Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques

Anti-retroviral therapy (ART) has been highly successful in controlling HIV replication, reducing viral burden, and preventing both progression to AIDS and viral transmission. Yet, ART alone cannot cure the infection. Even after years of successful therapy, ART withdrawal leads inevitably to viral r...

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Detalles Bibliográficos
Autores principales: Virnik, Konstantin, Rosati, Margherita, Medvedev, Alexei, Scanlan, Aaron, Walsh, Gabrielle, Dayton, Frances, Broderick, Kate E., Lewis, Mark, Bryson, Yvonne, Lifson, Jeffrey D., Ruprecht, Ruth M., Felber, Barbara K., Berkower, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055890/
https://www.ncbi.nlm.nih.gov/pubmed/32130229
http://dx.doi.org/10.1371/journal.pone.0228163