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Mathematical modeling to reveal breakthrough mechanisms in the HIV Antibody Mediated Prevention (AMP) trials

The ongoing Antibody Mediated Prevention (AMP) trials will uncover whether passive infusion of the broadly neutralizing antibody (bNAb) VRC01 can protect against HIV acquisition. Previous statistical simulations indicate these trials may be partially protective. In that case, it will be crucial to i...

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Detalles Bibliográficos
Autores principales: Reeves, Daniel B., Huang, Yunda, Duke, Elizabeth R., Mayer, Bryan T., Cardozo-Ojeda, E. Fabian, Boshier, Florencia A., Swan, David A., Rolland, Morgane, Robb, Merlin L., Mascola, John R., Cohen, Myron S., Corey, Lawrence, Gilbert, Peter B., Schiffer, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055956/
https://www.ncbi.nlm.nih.gov/pubmed/32084132
http://dx.doi.org/10.1371/journal.pcbi.1007626