Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast

Septin proteins evolved from ancestral GTPases and co-assemble into hetero-oligomers and cytoskeletal filaments. In Saccharomyces cerevisiae, five septins comprise two species of hetero-octamers, Cdc11/Shs1–Cdc12–Cdc3–Cdc10–Cdc10–Cdc3–Cdc12–Cdc11/Shs1. Slow GTPase activity by Cdc12 directs the choic...

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Detalles Bibliográficos
Autores principales: Johnson, Courtney R, Steingesser, Marc G, Weems, Andrew D, Khan, Anum, Gladfelter, Amy, Bertin, Aurélie, McMurray, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056273/
https://www.ncbi.nlm.nih.gov/pubmed/31990274
http://dx.doi.org/10.7554/eLife.54355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056273/
https://www.ncbi.nlm.nih.gov/pubmed/31990274
http://dx.doi.org/10.7554/eLife.54355

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