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Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation
Transduction of extracellular matrix mechanics affects cell migration, proliferation, and differentiation. While this mechanotransduction is known to depend on the regulation of focal adhesion kinase phosphorylation on Y397 (FAKpY397), the mechanism remains elusive. To address this, we developed a m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056303/ https://www.ncbi.nlm.nih.gov/pubmed/32181337 http://dx.doi.org/10.1126/sciadv.aax1909 |