Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation

Transduction of extracellular matrix mechanics affects cell migration, proliferation, and differentiation. While this mechanotransduction is known to depend on the regulation of focal adhesion kinase phosphorylation on Y397 (FAKpY397), the mechanism remains elusive. To address this, we developed a m...

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Detalles Bibliográficos
Autores principales: Cheng, Bo, Wan, Wanting, Huang, Guoyou, Li, Yuhui, Genin, Guy M., Mofrad, Mohammad R. K., Lu, Tian Jian, Xu, Feng, Lin, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056303/
https://www.ncbi.nlm.nih.gov/pubmed/32181337
http://dx.doi.org/10.1126/sciadv.aax1909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056303/
https://www.ncbi.nlm.nih.gov/pubmed/32181337
http://dx.doi.org/10.1126/sciadv.aax1909

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