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MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

Although photodynamic therapy (PDT) has been clinically applied tumor hypoxia still greatly restricts the performance of this oxygen-dependent oncological treatment. The delivery of oxygen donors to tumor may produce excessive reactive oxygen species (ROS) and damage the peripheral tissues. Herein,...

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Detalles Bibliográficos
Autores principales: Zhao, Lingzhi, Li, Junyao, Su, Yaoquan, Yang, Liqiang, Chen, Liu, Qiang, Lei, Wang, Yajing, Xiang, Huijing, Tham, Huijun Phoebe, Peng, Juanjuan, Zhao, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056313/
https://www.ncbi.nlm.nih.gov/pubmed/32181355
http://dx.doi.org/10.1126/sciadv.aaz0575