Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics

Paramyxoviruses are negative-polarity RNA viruses of major clinical importance. The dynamic interaction of the RNA-dependent RNA polymerase (RdRP) complex with the encapsidated RNA genome is mechanistically and structurally poorly understood. Having generated recombinant measles (MeV) and canine dis...

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Detalles Bibliográficos
Autores principales: Sourimant, Julien, Thakkar, Vidhi D., Cox, Robert M., Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056317/
https://www.ncbi.nlm.nih.gov/pubmed/32181359
http://dx.doi.org/10.1126/sciadv.aaz1590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056317/
https://www.ncbi.nlm.nih.gov/pubmed/32181359
http://dx.doi.org/10.1126/sciadv.aaz1590

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