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Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells
When self-renewing pluripotent cells receive a differentiation signal, ongoing cell duplication needs to be coordinated with entry into a differentiation program. Accordingly, transcriptional activation of lineage specifier genes and cell differentiation is confined to the G(1) phase of the cell cyc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056320/ https://www.ncbi.nlm.nih.gov/pubmed/32181346 http://dx.doi.org/10.1126/sciadv.aay4768 |