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Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells

When self-renewing pluripotent cells receive a differentiation signal, ongoing cell duplication needs to be coordinated with entry into a differentiation program. Accordingly, transcriptional activation of lineage specifier genes and cell differentiation is confined to the G(1) phase of the cell cyc...

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Detalles Bibliográficos
Autores principales: Asenjo, Helena G., Gallardo, Amador, López-Onieva, Lourdes, Tejada, Irene, Martorell-Marugán, Jordi, Carmona-Sáez, Pedro, Landeira, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056320/
https://www.ncbi.nlm.nih.gov/pubmed/32181346
http://dx.doi.org/10.1126/sciadv.aay4768