Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse

FAH domain containing protein 1 (FAHD1) is a mammalian mitochondrial protein, displaying bifunctionality as acylpyruvate hydrolase (ApH) and oxaloacetate decarboxylase (ODx) activity. We report the crystal structure of mouse FAHD1 and structural mapping of the active site of mouse FAHD1. Despite hig...

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Detalles Bibliográficos
Autores principales: Weiss, Alexander K.H., Naschberger, Andreas, Cappuccio, Elia, Metzger, Christina, Mottes, Lorenza, Holzknecht, Max, von Velsen, Jill, Bowler, Matthew W., Rupp, Bernhard, Jansen-Dürr, Pidder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056447/
https://www.ncbi.nlm.nih.gov/pubmed/32068790
http://dx.doi.org/10.1042/BSR20194431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056447/
https://www.ncbi.nlm.nih.gov/pubmed/32068790
http://dx.doi.org/10.1042/BSR20194431

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