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Endoplasmic reticulum stress occurs in association with the extrusion of toxic extracellular vesicles from human placentae treated with antiphospholipid antibodies

Antiphospholipid autoantibodies (aPLs), a major maternal risk factor for preeclampsia, are taken into the syncytiotrophoblast where they bind intracellular vesicles and mitochondria. Subsequently, large quantities of extracellular vesicles (EVs) extruded from syncytiotrophoblast into the maternal ci...

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Detalles Bibliográficos
Autores principales: Tang, Yunhui, Chen, Yan, Nursalim, Yohanes, Groom, Katie, Hickey, Anthony, Chamley, Larry, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056451/
https://www.ncbi.nlm.nih.gov/pubmed/32068238
http://dx.doi.org/10.1042/CS20191245