Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase‐3β‐mediated activation of autophagy

BACKGROUND AND PURPOSE: Cerebral ischaemia/reperfusion causes exacerbated neuronal damage involving excessive autophagy and neuronal loss. The present study was designed to investigate the effect of icariside II, one of main active ingredients of Herba Epimedii on this loss and whether this is relat...

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Detalles Bibliográficos
Autores principales: Gao, Jianmei, Long, Long, Xu, Fan, Feng, Linying, Liu, Yuangui, Shi, Jingshan, Gong, Qihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056470/
https://www.ncbi.nlm.nih.gov/pubmed/31658364
http://dx.doi.org/10.1111/bph.14912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056470/
https://www.ncbi.nlm.nih.gov/pubmed/31658364
http://dx.doi.org/10.1111/bph.14912

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