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Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase‐3β‐mediated activation of autophagy
BACKGROUND AND PURPOSE: Cerebral ischaemia/reperfusion causes exacerbated neuronal damage involving excessive autophagy and neuronal loss. The present study was designed to investigate the effect of icariside II, one of main active ingredients of Herba Epimedii on this loss and whether this is relat...
Autores principales: | Gao, Jianmei, Long, Long, Xu, Fan, Feng, Linying, Liu, Yuangui, Shi, Jingshan, Gong, Qihai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056470/ https://www.ncbi.nlm.nih.gov/pubmed/31658364 http://dx.doi.org/10.1111/bph.14912 |
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