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Nrf2 is required for suppressing osteoclast RANKL-induced differentiation in RAW 264.7 cells via inactivating cannabinoid receptor type 2 with AM630

OBJECTIVE: Nuclear factor-erythroid 2-related factor 2 (Nrf2) is shown to as a negative-regulatory cause in osteoclasts differentiation. Cannabinoid receptor type 2 (CB2) is verified to regulate osteoclast differentiation, though with diversed results. METHODS: In current research, we studied the Nr...

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Detalles Bibliográficos
Autores principales: Li, Wan, Sun, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056625/
https://www.ncbi.nlm.nih.gov/pubmed/32154333
http://dx.doi.org/10.1016/j.reth.2020.02.001