The lncRNA-GAS5/miR-221-3p/DKK2 Axis Modulates ABCB1-Mediated Adriamycin Resistance of Breast Cancer via the Wnt/β-Catenin Signaling Pathway

Drug resistance, including adriamycin (ADR)-based therapeutic resistance, is a crucial cause of chemotherapy failure in breast cancer treatment. Acquired chemoresistance has been identified to be closely associated with the overexpression of P-glycoprotein (P-gp/ABCB1). Long non-coding RNA (lncRNA)...

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Detalles Bibliográficos
Autores principales: Chen, Zhaolin, Pan, Tingting, Jiang, Duochen, Jin, Le, Geng, Yadi, Feng, Xiaojun, Shen, Aizong, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056627/
https://www.ncbi.nlm.nih.gov/pubmed/32160712
http://dx.doi.org/10.1016/j.omtn.2020.01.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056627/
https://www.ncbi.nlm.nih.gov/pubmed/32160712
http://dx.doi.org/10.1016/j.omtn.2020.01.030

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