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Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis

Children and adolescents with major depressive disorder (MDD) appear to be more responsive to placebo than adults in randomized placebo-controlled trials (RCTs) of second and newer generation antidepressants (SNG-AD). Previous meta-analyses obtained conflicting results regarding modifiers. We aimed...

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Detalles Bibliográficos
Autores principales: Meister, Ramona, Abbas, Mariam, Antel, Jochen, Peters, Triinu, Pan, Yiqi, Bingel, Ulrike, Nestoriuc, Yvonne, Hebebrand, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056684/
https://www.ncbi.nlm.nih.gov/pubmed/30535589
http://dx.doi.org/10.1007/s00787-018-1244-7