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Intradermal Immunization of EBOV VLPs in Guinea Pigs Induces Broader Antibody Responses Against GP Than Intramuscular Injection

Ebolavirus (EBOV) infection in humans causes severe hemorrhagic fevers with high mortality rates that range from 30 to 80% as shown in different outbreaks. Thus the development of safe and efficacious EBOV vaccines remains an important goal for biomedical research. We have shown in early studies tha...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Wen, Zhiyuan, Carrion, Ricardo, Nunneley, Jerritt, Staples, Hilary, Ticer, Anysha, Patterson, Jean L., Compans, Richard W., Ye, Ling, Yang, Chinglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056717/
https://www.ncbi.nlm.nih.gov/pubmed/32174901
http://dx.doi.org/10.3389/fmicb.2020.00304