Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors

Cyclin-dependent kinases (CDKs) constitute a family of 20 serine/threonine protein kinases that play pivotal roles in the regulation of numerous important molecular and cellular processes. CDKs have long been considered promising therapeutic targets in a variety of pathologies, and the recent therap...

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Detalles Bibliográficos
Autores principales: Robert, Thomas, Johnson, Jared L., Guichaoua, Roxane, Yaron, Tomer M., Bach, Stéphane, Cantley, Lewis C., Colas, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056863/
https://www.ncbi.nlm.nih.gov/pubmed/32175313
http://dx.doi.org/10.3389/fchem.2020.00147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056863/
https://www.ncbi.nlm.nih.gov/pubmed/32175313
http://dx.doi.org/10.3389/fchem.2020.00147

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