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Analysing central metabolism in ultra-high resolution: At the crossroads of carbon and nitrogen
BACKGROUND: Cancer cell metabolism can be characterised by adaptive metabolic alterations, which support abnormal proliferative cell growth with high energetic demand. De novo nucleotide biosynthesis is essential for providing nucleotides for RNA and DNA synthesis, and drugs targeting this biosynthe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056925/ https://www.ncbi.nlm.nih.gov/pubmed/31928927 http://dx.doi.org/10.1016/j.molmet.2019.12.002 |