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Targeting extracellular nutrient dependencies of cancer cells

BACKGROUND: Cancer cells rewire their metabolism to meet the energetic and biosynthetic demands of their high proliferation rates and environment. Metabolic reprogramming of cancer cells may result in strong dependencies on nutrients that could be exploited for therapy. While these dependencies may...

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Detalles Bibliográficos
Autores principales: Garcia-Bermudez, Javier, Williams, Robert T., Guarecuco, Rohiverth, Birsoy, Kıvanç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056928/
https://www.ncbi.nlm.nih.gov/pubmed/31926876
http://dx.doi.org/10.1016/j.molmet.2019.11.011