Thermal proteome profiling for interrogating protein interactions

Thermal proteome profiling (TPP) is based on the principle that, when subjected to heat, proteins denature and become insoluble. Proteins can change their thermal stability upon interactions with small molecules (such as drugs or metabolites), nucleic acids or other proteins, or upon post‐translatio...

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Detalles Bibliográficos
Autores principales: Mateus, André, Kurzawa, Nils, Becher, Isabelle, Sridharan, Sindhuja, Helm, Dominic, Stein, Frank, Typas, Athanasios, Savitski, Mikhail M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057112/
https://www.ncbi.nlm.nih.gov/pubmed/32133759
http://dx.doi.org/10.15252/msb.20199232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057112/
https://www.ncbi.nlm.nih.gov/pubmed/32133759
http://dx.doi.org/10.15252/msb.20199232

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